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. CRK12:CYC9 interact in a very yeast two-hybrid assay and form an Lively protein kinase complex in procyclic and bloodstream form T. brucei, is unfold by the tsetse fly and results in trypanosomiasis in individuals and animals. Both the life cycle and mobile cycle on the parasite are complicated. Trypanosomes have eleven cdc2-similar kinases (CRKs